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1

Structure and Regulation of Soluble Guanylate Cyclase

Derbyshire, Emily R., Marletta, Michael A.

Journal:

Annual Review of Biochemistry

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

2

Enhancing horizon scanning by utilizing pre-developed scenarios: Analysis of current practice and specification of a process improvement to aid the identification of important ‘weak signals’

Rowe, Emily, Wright, George, Derbyshire, James

Journal:

Technological Forecasting and Social Change

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

3

Closing in on a new treatment for sleeping sickness

Derbyshire, Emily R, Clardy, Jon

Journal:

Year:

2013

File:

PDF, 1.07 MB

2013

4

Synthesis and Analysis of Natural Product‐Like Macrocycles via Tandem Oxidation/Oxa‐Conjugate Addition Reactions

Hong, Jiyong, Lee, Hyunji, Sylvester, Kayla, Derbyshire, Emily

Journal:

Chemistry - A European Journal

Year:

2019

Language:

english

File:

PDF, 1.50 MB

english, 2019

5

Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy

Lu, Kuan-Yi, Quan, Baiyi, Sylvester, Kayla, Srivastava, Tamanna, Fitzgerald, Michael C., Derbyshire, Emily R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 1.35 MB

2020

6

Synthesis and evaluation of a phosphonate analogue of the soluble guanylate cyclase activator YC-1

Nathaniel I. Martin, Emily R. Derbyshire, Michael A. Marletta

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

7

Molecular steps in sGC activation

Elizabeth M Boon, Stephen PL Cary, Shirley H Huang, Jonathan A Winger, Emily R Derbyshire, Mark S Price, William K Erbil, Michael A Marletta

Journal:

BMC Pharmacology

Year:

2007

Language:

english

File:

PDF, 729 KB

english, 2007

8

A molecular view of the regulation of sGC activity

Michael A Marletta, Emily R Derbyshire, W Kaya Erbil, Nathaniel B Fernhoff, John Kuriyan, Charles Olea, Mark S Price, David E Wemmer

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 225 KB

english, 2009

9

The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase

Jonathan A Winger, Emily R Derbyshire, Meindert H Lamers, Michael A Marletta, John Kuriyan

Journal:

BMC Structural Biology

Year:

2008

Language:

english

File:

PDF, 2.11 MB

english, 2008

10

Characterization of Plasmodium Liver Stage Inhibition by Halofuginone

Dr. Emily R. Derbyshire, Prof. Dr. Ralph Mazitschek, Prof. Dr. Jon Clardy

Journal:

Year:

2012

Language:

english

File:

PDF, 552 KB

english, 2012

11

Cover Picture: Characterization of Plasmodium Liver Stage Inhibition by Halofuginone (ChemMedChem 5/2012)

Dr. Emily R. Derbyshire, Prof. Dr. Ralph Mazitschek, Prof. Dr. Jon Clardy

Journal:

Year:

2012

Language:

english

File:

PDF, 729 KB

english, 2012

12

Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc1 Inhibitors

Carolyn K. Dong, Sameer Urgaonkar, Joseph F. Cortese, Francisco-Javier Gamo, Jose F. Garcia-Bustos, Maria J. Lafuente, Vishal Patel, Leila Ross, Bradley I. Coleman, Emily R. Derbyshire, Clary B. Clish

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1012 KB

english, 2011

13

Nitric oxide signaling: no longer simply on or off

Stephen P.L. Cary, Jonathan A. Winger, Emily R. Derbyshire, Michael A. Marletta

Journal:

Trends in Biochemical Sciences

Year:

2006

Language:

english

File:

PDF, 1.70 MB

english, 2006

14

Antibiotic and Antimalarial Quinones from Fungus-Growing Ant-Associated Pseudonocardia sp.

Carr, Gavin, Derbyshire, Emily R., Caldera, Eric, Currie, Cameron R., Clardy, Jon

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 253 KB

english, 2012

15

The Next Opportunity in Anti-Malaria Drug Discovery: The Liver Stage

Derbyshire, Emily R., Mota, Maria M., Clardy, Jon, Rall, Glenn F.

Journal:

Year:

2011

Language:

english

File:

PDF, 202 KB

english, 2011

16

Nucleotide Regulation of Soluble Guanylate Cyclase Substrate Specificity

Derbyshire, Emily R., Fernhoff, Nathaniel B., Deng, Sarah, Marletta, Michael A.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.16 MB

english, 2009

17

Probing Domain Interactions in Soluble Guanylate Cyclase

Derbyshire, Emily R., Winter, Michael B., Ibrahim, Mohammed, Deng, Sarah, Spiro, Thomas G., Marletta, Michael A.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.41 MB

english, 2011

18

Chemical Interrogation of the Malaria Kinome

Derbyshire, Emily R., Zuzarte-Luís, Vanessa, Magalhães, Andreia D., Kato, Nobutaka, Sanschagrin, Paul C., Wang, Jinhua, Zhou, Wenjun, Miduturu, Chandrasekhar V., Mazitschek, Ralph, Sliz, Piotr, Mota,

Journal:

Year:

2014

Language:

english

File:

PDF, 1.25 MB

english, 2014

19

Soluble Guanylate Cyclase Is Activated Differently by Excess NO and by YC-1: Resonance Raman Spectroscopic Evidence

Ibrahim, Mohammed, Derbyshire, Emily R., Soldatova, Alexandra V., Marletta, Michael A., Spiro, Thomas G.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.10 MB

english, 2010

20

Probing Soluble Guanylate Cyclase Activation by CO and YC-1 Using Resonance Raman Spectroscopy

Ibrahim, Mohammed, Derbyshire, Emily R., Marletta, Michael A., Spiro, Thomas G.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.41 MB

english, 2010

21

Characterization of Nitrosoalkane Binding and Activation of Soluble Guanylate Cyclase †

Derbyshire, Emily R., Tran, Rosalie, Mathies, Richard A., Marletta, Michael A.

Journal:

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

22

Characterization of Two Different Five-Coordinate Soluble Guanylate Cyclase Ferrous–Nitrosyl Complexes †

Derbyshire, Emily R., Gunn, Alexander, Ibrahim, Mohammed, Spiro, Thomas G., Britt, R. David, Marletta, Michael A.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

23

Conformationally Distinct Five-Coordinate Heme–NO Complexes of Soluble Guanylate Cyclase Elucidated by Multifrequency Electron Paramagnetic Resonance (EPR)

Gunn, Alexander, Derbyshire, Emily R., Marletta, Michael A., Britt, R. David

Journal:

Year:

2012

Language:

english

File:

PDF, 887 KB

english, 2012

24

Cover Picture: Chemical Interrogation of the Malaria Kinome (ChemBioChem 13/2014)

Derbyshire, Emily R., Zuzarte-Luís, Vanessa, Magalhães, Andreia D., Kato, Nobutaka, Sanschagrin, Paul C., Wang, Jinhua, Zhou, Wenjun, Miduturu, Chandrasekhar V., Mazitschek, Ralph, Sliz, Piotr, Mota,

Journal:

Year:

2014

Language:

english

File:

PDF, 512 KB

english, 2014

25

Discovery of Dual Stage Malaria Inhibitors with New Targets

Raphemot, Rene, Lafuente-Monasterio, Maria J., Gamo-Benito, Francisco Javier, Clardy, Jon, Derbyshire, Emily R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 689 KB

english, 2015

26

Optimising therapeutic effect of aurora B inhibition in acute myeloid leukemia with AZD2811 nanoparticles

Floc'h, Nicolas, Ashton, Susan, Taylor, Paula, Trueman, Dawn, Harris, Emily, Odedra, Rajesh, Maratea, Kim, Derbyshire, Nicola, Caddy, Jacqueline, Jacobs, Vivien N., Hattersley, Maureen, Wen, Shenghua,

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 565 KB

english, 2017

27

Review of King Lear (directed by Tom Morris for the Bristol Old Vic/ Bristol Old Vic Theatre School) at Bristol Old Vic, King Street, Bristol, 28 June 2016

Derbyshire, Emily

Journal:

Year:

2017

Language:

english

File:

PDF, 474 KB

english, 2017

28

Exploring the untapped biosynthetic potential of apicomplexan parasites

Ganley, Jack, Toro-Moreno, Maria, Derbyshire, Emily R.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.43 MB

english, 2017

29

Identification of Hsp90 inhibitors with anti- Plasmodium activity

Posfai, Dora, Eubanks, Amber L., Keim, Allison I., Lu, Kuan-Yi, Wang, Grace Z., Hughes, Philip F., Kato, Nobutaka, Haystead, Timothy A., Derbyshire, Emily R.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2018

Language:

english

File:

PDF, 1.55 MB

english, 2018

30

Discovery of antimicrobial lipodepsipeptides produced by a Serratia sp. within mosquito microbiomes

Ganley, Jack, Carr, Gavin, Ioerger, Thomas, Sacchettini, James, Clardy, Jon, Derbyshire, Emily

Journal:

Year:

2018

Language:

english

File:

PDF, 1.82 MB

english, 2018

31

Review of Shakespeare’s Othello (directed by Richard Twyman for Shakespeare at the Tobacco Factory and Tobacco Factory Theatres) at the Tobacco Factory, Raleigh Road, Bristol, 21 February 2017; and Othello (directed by Ellen McDougall for Shakespeare’s Globe) at the Sam Wanamaker Playhouse, New Globe Walk, London, 8 April 2017

Derbyshire, Emily

Journal:

Year:

2017

Language:

english

File:

PDF, 490 KB

english, 2017

32

Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection

Posfai, Dora, Sylvester, Kayla, Reddy, Anupama, Ganley, Jack G., Wirth, Johannes, Cullen, Quinlan E., Dave, Tushar, Kato, Nobutaka, Dave, Sandeep S., Derbyshire, Emily R., Heussler, Volker Theo

Journal:

Year:

2018

Language:

english

File:

PDF, 9.54 MB

english, 2018

33

Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes

Ganley, Jack G., Carr, Gavin, Ioerger, Thomas R., Sacchettini, James C., Clardy, Jon, Derbyshire, Emily R.

Journal:

Year:

2018

File:

PDF, 519 KB

2018

34

Evaluating treatment outcomes for young people participating in a high-intensity therapeutic violence intervention in the English Youth Custody Service

Derbyshire, Jonathan M., Tarrant, Emily, Fitter, Ruby, Gibson, Rachel A.

Journal:

Legal and Criminological Psychology

Year:

2018

Language:

english

File:

PDF, 238 KB

english, 2018

35

In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors

Eubanks, Amber, Perkins, Marisha, Sylvester, Kayla, Ganley, Jack, Posfai, Dora, Sanschargrin, Paul, Hong, Jiyong, Sliz, Piotrek, Derbyshire, Emily

Journal:

Year:

2018

Language:

english

File:

PDF, 2.47 MB

english, 2018

36

Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites

Raphemot, Rene, Eubanks, Amber Leigh, Toro-Moreno, Maria, Geiger, Rechel Anne, Hughes, Philip Floyd, Lu, Kuan-Yi, Haystead, Timothy Arthur James, Derbyshire, Emily Rose

Journal:

Cell Chemical Biology

Year:

2018

Language:

english

File:

PDF, 2.57 MB

english, 2018

37

Synthesis and Analysis of Natural Product‐Like Macrocycles via Tandem Oxidation/Oxa‐Conjugate Addition Reactions

Hong, Jiyong, Lee, Hyunji, Sylvester, Kayla, Derbyshire, Emily

Journal:

Chemistry - A European Journal

Year:

2019

File:

PDF, 1.50 MB

2019

38

Closing in on a new treatment for sleeping sickness

Derbyshire, Emily R, Clardy, Jon

Journal:

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

39

Review of Shakespeare's Macbeth (directed by Adele Thomas for Tobacco Factory Theatres) at the Tobacco Factory, Bristol, 26 February 2018

Derbyshire, Emily

Journal:

Year:

2018

File:

PDF, 534 KB

2018

40

Close the ring to break the cycle: Tandem quinolone-alkyne-cyclisation gives access to tricyclic pyrrolo[1,2-a]quinolin-5-ones with potent anti-protozoal activity

Szamosvari, David, Sylvester, Kayla, Schmid, Philipp, Lu, Kuan-Yi, Derbyshire, Emily, Böttcher, Thomas

Journal:

Chemical Communications

Year:

2019

Language:

english

File:

PDF, 675 KB

english, 2019

41

Discovery of Druggable Host Factors Critical to Plasmodium Liver-Stage Infection

Raphemot, Rene, Toro-Moreno, Maria, Lu, Kuan-Yi, Posfai, Dora, Derbyshire, Emily Rose

Journal:

Cell Chemical Biology

Year:

2019

Language:

english

File:

PDF, 2.87 MB

english, 2019

42

Investigating the Role of Class I Adenylate-Forming Enzymes in Natural Product Biosynthesis

D’Ambrosio, Hannah K., Derbyshire, Emily R.

Journal:

ACS Chemical Biology

Year:

2019

File:

PDF, 992 KB

2019

43

Coculturing of Mosquito‐Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis

Ganley, Jack, D’Ambrosio, Hannah K, Shieh, Meg, Derbyshire, Emily

Journal:

Year:

2019

File:

PDF, 3.55 MB

2019

44

Linking Genes to Molecules in Eukaryotic Sources: An Endeavor to Expand Our Biosynthetic Repertoire

Ganley, Jack G., Derbyshire, Emily R.

Journal:

Year:

2020

Language:

english

File:

PDF, 1.97 MB

english, 2020

45

Itâs about Time: Insights into the Modes of Action of Antimalarials

Toro-Moreno, Maria, Derbyshire, Emily R.

Journal:

Cell Chemical Biology

Year:

2020

Language:

english

File:

PDF, 485 KB

english, 2020

46

Tafenoquine: A Step toward Malaria Elimination

Lu, Kuan-Yi, Derbyshire, Emily R.

Journal:

Year:

2020

Language:

english

File:

PDF, 1.29 MB

english, 2020

47

RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection

Toro-Moreno, Maria, Sylvester, Kayla, Srivastava, Tamanna, Posfai, Dora, Derbyshire, Emily R., Boothroyd, John C.

Journal:

Year:

2020

File:

PDF, 4.00 MB

2020

48

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

Posfai, Dora, Maher, Steven P., Roesch, Camille, Vantaux, AmÃ©lie, Sylvester, Kayla, PÃ©neau, Julie, Popovici, Jean, Kyle, Dennis E., Witkowski, BenoÃ®t, Derbyshire, Emily R.

Journal:

Cell Chemical Biology

Year:

2020

File:

PDF, 2.69 MB

2020

49

Cover Feature: Coculturing of MosquitoâMicrobiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis (ChemBioChem 9/2020)

Ganley, Jack G., D'Ambrosio, Hannah K., Shieh, Meg, Derbyshire, Emily R.

Journal:

Year:

2020

File:

PDF, 1.22 MB

2020

50

A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity

Ganley, Jack G., Pandey, Ashmita, Sylvester, Kayla, Lu, Kuan-Yi, Toro-Moreno, Maria, RÃ¼tschlin, Sina, Bradford, James M., Champion, Cody J., BÃ¶ttcher, Thomas, Xu, Jiannong, Derbyshire, Emily R.

Journal:

Cell Chemical Biology

Year:

2020

File:

PDF, 2.79 MB

2020

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